If an opening falls outside rated firestop work, decide what kind of path you are looking at: a shared-wall air path or a concealed fireblocking gap.
When the path runs through a shared wall, trace where air moves after it passes the visible gap. It may continue through a chase, ceiling space, service cavity, or mechanical boundary before it reaches another space.
For commercial air sealing, follow the air-sealing detail shown for the wall, floor, or mechanical boundary you are working on. Your goal is to close the connected path without changing what the assembly needs to do. Mechanical rooms need a closer look because MEP and low-voltage penetrations often share the same boundary.
When the path enters a rated wall, treat it as firestop work first. When it remains a non-rated shared-wall path, air sealing can reduce routes for smoke, fumes, and nuisance odors between spaces.